The challenges of working with traditional chromatography columns and beads have been well documented as the bioprocess industry drives towards a more flexible manufacturing paradigm. A new single-use (per batch) chromatography platform from Natrix Separations promises to enable greater flexibility and economic effectiveness for downstream operations.
In this webinar, Dr. Jim Stout, Vice President of Process Sciences at Natrix Separations will walk you through the mechanical and chemical composition of a new membrane chromatography technology that maintains high binding capacity and resolution at very high flow rates (residence time ≤ 10 seconds). Data will be shared that illustrate mAb purification performance for both capture (binding) and polish (binding and flow-through) purification modes using HD-C (weak cation exchange), HD-Sb (mixed mode), and HD-Q (strong anion exchange) membrane chemistries.
Register today to learn about the future of mAb purification and the move toward a fully integrated single-use-per-batch platform.
James G. Stout, Ph.D.,
Vice President, Process Sciences at Natrix Separations, Inc.
Dr. Stout is responsible for all aspects of process development and process science for Natrix HD membrane technology.
Dr. Stout earned his Ph.D. in Chemistry at the University of Cincinnati, and was an NIH Post-Doctoral Fellow at the University of Cincinnati College of Medicine, Department of Pharmacology & Cell Biophysics. He holds a B.S. in Chemistry from Denison University. He is the inventor of record on several U.S. patents, and is co-author of 18 peer-reviewed publications.
Over the past 15 years, Dr. Stout established himself as a downstream process and technology leader in the biopharmaceutical industry. His recent positions include Director of Process Science & Engineering at ImmunoGen; Associate Director of Process Development at Shire HGT; Director, Purification Sciences at Amgen; Group Leader of Purification Process Sciences at the Abbott Bioresearch Center; as well as process development positions at Medarex and Alexion.
5295 John Lucas Drive, Burlington, ON Canada, email: stout@natrixseparations.com.
- Understand how Natrix technology delivers resin binding capacity at membrane flow rates
- Learn how this disruptive technology is making downstream processing more flexible
- Discover how this high-capacity high-speed technology scales from the lab to the GMP facility
- See how this salt-tolerant technology is being developed across major chromatography chemistries
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- Manufacturing Sciences and Technology
