Tangential flow filtration is commonly used in bioprocessing for applications such as process stream clarification, cell therapy harvests, protein concentration and diafiltration. Applying single-use technologies to this step confers significant benefits including increasing flexibility and reducing time to market through the elimination of cleaning validation programs.
In this webinar you will learn how to select, size and scale the most appropriate TFF filter for your application. Critically this ensures both development and subsequent manufacturing costs are optimized. We will describe how the selected filter must be integrated into a single-use manifold in such a way that automation can be applied to ensure process consistency and control.
You will learn what points should be considered in determining the level of automation required for your application such as operational preferences and the environment in which the equipment will be used. We will describe the sophisticated control strategies and innovative Process Analytical Technologies (PAT) such as GMP-ready, single-use sensors that can be integrated into single-use TFF steps. These technologies can greatly enhance control and thereby reduce the cost of poor quality associated with the closing of deviations prior to lot release.
Register now for this webinar if you are considering or in the process of implementing single-use TFF operations within your bioprocess.
Nick Hutchinson,
Global Market Development Manager
Dr Nick Hutchinson has a Masters and Doctorate in Biochemical Engineering from University College London, UK where he focused on laboratory tools for rapid bioprocess development and characterization. He then worked at Lonza Biologics in an R&D function investigating novel methods for large-scale antibody purification before moving to an operational role scaling-up and transferring manufacturing processes between Lonza sites in the UK, Spain and USA.
Nick now works in Market Development at Parker domnick hunter where his focus is in bringing Parker's strengths in Motion & Control to Bioprocessing. This will enable customers to improve the quality and deliverability of existing and future biopharmaceuticals.
- Understand the benefits of single-use TFF technologies
- Learn how to correctly select, size and scale TFF filters for single-use applications
- Learn how to determine the optimum single-use TFF automation strategy
- Understand how single-use sensor technology can be applied to enhance process control
- Purification Scientists
- Downstream Process Development
- Operations Managers
- Manufacturing Science and Technology
- Automation Engineers
