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Stacy Holdread, MS
Staff Scientist

The Science of Cell Culture Media Manufacturing

Webinars

The composition of cell culture media has evolved significantly from simple classical formulations, such as Eagle's Minimum Essential Medium (EMEM), to more complex and highly specialized formulations.

Such progress in cell culture media formulation requires innovative technology and knowledge for the development and manufacturing of formulations that contain intricate complexities including chemical interactions, content uniformity, solubility and stability. Since cell culture media is utilized as a raw material for the production of human and animal therapeutics, the highest consistency of formulation is required.

During this educational webinar hosted by BD, you will learn how a manufacturing process with broad application to both simple and complex cell culture media formulations can be designed and developed to ensure product quality and consistency is preserved.

The webinar will highlight how chemical and physical properties of raw materials and the desired final product and process characteristics influence the design of an optimal process for manufacturing cell culture media for bioproduction applications.

Presented by

Stacy Holdread, MS

Staff Scientist

Stacy Holdread is a Staff Scientist in the BD Biosciences Advanced Bioprocessing R&D group with almost 25 years of experience in mammalian and microbial media design and manufacture. She worked on microbial media optimization and peptone development at Difco Laboratories for three years prior to joining the BD cell culture team. Since joining BD, she helped to establish BD's mammalian cell culture media design program focused on the development of media, feeds, supplements, and processes for bioproduction applications. Ms. Holdread also played a key role in establishing BD's scalable manufacturing process which encompasses product development, piloting, and GMP production. In addition to her product development responsibilities, Ms. Holdread continues to manage BD's technical transfer process and provides technical manufacturing support.

Ms. Holdread received her BS in Biology from the University of Michigan and her MS in Biotechnology from The Johns Hopkins University.

Learning objectives
  • Understand better how chemical and physical properties of raw materials can influence the media manufacturing process
  • Learn how a media manufacturing process can be designed and developed to ensure product quality and consistency
Audience
  • Process Development
  • Senior Scientist
  • Research and Development
  • Lab Manager
  • Manufacturing Sciences
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